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The occurrence of the 15;17 translocation in acute promyelocytic leukemia

✍ Scribed by M. De Braekeleer; C.C. Lin

Book ID: 119103192
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 563 KB
Volume: 19
Category: Article
ISSN: 0165-4608
DOI: 10.1016/0165-4608(86)90060-9

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Acute promyelocytic leukemia (APL) is a morphologically distinct subtype of acute nonlymphocytic leukemia (ANLL) characterized cytogenetically by the presence of a translocation between chromosomes 15 and 17 (t(15;17)). In contrast to other subtypes of ANLL, morphologic examination of the bone marro