𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthetic studies on mitomycins synthesis of aziridino-pyrrolo(1,2-a)indoles.

✍ Scribed by Tadashi Hirata; Yasuhiro Yamada; Masanao Matsui


Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
191 KB
Volume
10
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


Synthetic approaches toward mitomyoins (I) (1) have been made energetically by a Lederle group snd the synthesis of 7-methoxymitosene (II) was reported (2). However, their various


πŸ“œ SIMILAR VOLUMES


Synthetic studies on substituted 9h-pyrr
✍ Yasuhiro Yamada; Tadashi Hirata; Masanao Matsui πŸ“‚ Article πŸ“… 1969 πŸ› Elsevier Science 🌐 French βš– 160 KB

## Mitomycin antibiotics (I) have a novel ring system that is aziridinopyrrolo II 1,2-a indoloquinone(1). In synthetic studies on mitomycin analogs Lederle group synthesised 7-benzyloxy-9H-pyrrolo 1,2-a indole(2) and substituted 2,3r.

A novel synthetic approach to mitomycins
✍ J. Geevers; G.W. Visser; D.N. Reinhoudt πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 200 KB

## Abstract A new method for the synthesis of pyrrolo[1,2‐__a__]indoles, starting from enamines via 1,5‐dipolar cyclization is described. The method is considered to be useful for the synthesis of mitomycin type of compounds.

Synthesis of pyrrolo[1,2-a]benzo[f]indol
✍ Vincenzo Carelli; Mario Cardellini; Flaviano Morlacchi πŸ“‚ Article πŸ“… 1967 πŸ› Elsevier Science 🌐 French βš– 210 KB

Considerable attention has been given during the last decade to some metabolic products of a group of Streptomyces, "the mitomycines", which show remarkable antibiotic and antitumoral activity.