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A novel synthetic approach to mitomycins. One step synthesis of a 5,10-dioxo-1H-pyrrolo[1,2-a]benz[f]indole

✍ Scribed by J. Geevers; G.W. Visser; D.N. Reinhoudt

Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 200 KB
Volume: 98
Category: Article
ISSN: 0165-0513
DOI: 10.1002/recl.19790980421

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✦ Synopsis

Abstract

A new method for the synthesis of pyrrolo[1,2‐a]indoles, starting from enamines via 1,5‐dipolar cyclization is described. The method is considered to be useful for the synthesis of mitomycin type of compounds.

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