Synthesis of α-Hydroxyacetophenones
✍ Scribed by McLaughlin, Mark; Belyk, Kevin M.; Qian, Gang; Reamer, Robert A.; Chen, Cheng-yi
- Book ID
- 111937133
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 446 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
## Abstract The title compound 1 undergoes cyclization and self‐condensation in the presence of dil. NaOH yielding chromone (2) and/or 1‐(3‐chromonyl)‐2‐(2‐hydroxybenzoyl)ethene (3). With benzaldehyde in the presence of piperidine in boiling ethanol, 1 reacts both by cyclization, and self‐condensat
Synthesis of ortho-hydroxyacetophenone derivatives 5 was carried out from the reaction of Baylis-Hillman acetates 1 and active methylene compounds 2 in N,N-dimethylformamide in the presence of K 2 CO 3 .