Synthesis of ortho-hydroxyacetophenone derivatives from Baylis–Hillman acetates

✍ Scribed by Jae Nyoung Kim; Yang Jin Im; Jeong Mi Kim

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 78 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01441-7

✦ Synopsis

Synthesis of ortho-hydroxyacetophenone derivatives 5 was carried out from the reaction of Baylis-Hillman acetates 1 and active methylene compounds 2 in N,N-dimethylformamide in the presence of K 2 CO 3 .