On the chemistry of α-formyl-2-hydroxyacetophenone

✍ Scribed by Széll, T. ;Sohár, P. ;Horváth, Gy.

• Book ID: 102368191
• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 169 KB
• Volume: 1995
• Category: Article
• ISSN: 0947-3440
• DOI: 10.1002/jlac.1995199511286

✦ Synopsis

Abstract

The title compound 1 undergoes cyclization and self‐condensation in the presence of dil. NaOH yielding chromone (2) and/or 1‐(3‐chromonyl)‐2‐(2‐hydroxybenzoyl)ethene (3). With benzaldehyde in the presence of piperidine in boiling ethanol, 1 reacts both by cyclization, and self‐condensation combined with cyclization to give 2, 3 and bis(3‐chromonyl‐phenyl)methane (5). If less than 0.1 M aq. NaOH is used 1 and benzaldehyde produces 3‐(α‐hydroxybenzoyl)chromone (4) which can also be converted into 5.