Compound \_7 (l',l'-D2-a-T) (see Scheme 3) was synthesized ( 9 ) via a sodium methoxide/CH,OD ring-opening of the methyl ester, 1'7, to give the 4 5.
Synthesis of α- and γ-tocopherols selectively labelled with deuterium
✍ Scribed by L. Hughes; M. Slaby; G. W. Burton; K. U. Ingold
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 350 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Four deuterium‐substituted α‐tocopherols (dideutero‐RRR, nonadeutero‐ambo, nonadeutero‐all‐rac and undecadeutero‐all‐rac) and a dideutero‐RRR‐γ‐tocopherol have been synthesized for use in studies of the biokinetics, bioavailability and metabolism of vitamin E.
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