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Synthesis of the Pentacyclic Skeleton of the Indole Alkaloid Arboflorine

โœ Scribed by Leal, Raul A.; Beaudry, Danial R.; Alzghari, Saeed K.; Sarpong, Richmond


Book ID
126424966
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
396 KB
Volume
14
Category
Article
ISSN
1523-7060

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Synthesis of the Pentacyclic Xestobergsterol Skeleton. -The key steps in the synthesis of the pentacyclic skeleton (X) are stereoselective formation of the ynol (VII) and intramolecular Pauson-Khand reaction of the enyne (VIII). Xestobergsterol is a histamine release inhibitor. -(KRAFFT,