synthesis of sempervirine, a pentacyclic anhydronium indole alkaloid
β Scribed by A. Chatterjee; A. Sahu; M. Saha; J. Banerji
- Book ID
- 104950451
- Publisher
- Springer Vienna
- Year
- 1996
- Tongue
- English
- Weight
- 249 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0026-9247
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Our recently synthesized' pentacyclic ester lactam(l) represents a central intermediate for preparing, with proper structural variations, reserpinoid and yohimbinoid molecules2 since itsD/E ring junction reduces cis 1 while maintaining an epimerizable C20 hydrogen for possible conversion toD/E trans
Three pentacyclic indole alkaloids, one novel named darcyribeirine (1) and the known isoreserpiline (2) and isoreserpine (3), were isolated from the root bark of the Rauvolfia grandiflora Mart. The structures were established by spectroscopic data.