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Synthesis of possible metabolites of chlorpromazine. V. 3,7-Disubstituted chlorpromazine derivatives

โœ Scribed by Edward A. Nodiff; Takanori Hayazaki; Toshiyuki Ito; Hoshyari L. Sharma; Tetsuya Kohno; Taisei Veda; Shiro Morosawa; Albert A. Manian


Book ID
112122562
Publisher
Journal of Heterocyclic Chemistry
Year
1971
Tongue
English
Weight
252 KB
Volume
8
Category
Article
ISSN
0022-152X

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โœ J. Cymerman Craig; L. D. Gruenke; S.-Y. Catherine Lee ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 325 KB

The eyntheeie of 2-chloro-10-(3'-dimethylaminopropyl)phenothiazine-3', 3'-d2 (Chlorpromazine-d2) and ite four major metabolitee (the mono-and didemethylated aminee, chlorpromazine sulfoxide, and chlorpromazine N-oxide), all containing the 3',3'-d2 label in > 95% ieotopic purity, ie deecribed. Consid