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The Synthesis of possible di- and trihydroxylated chlorpromazine metabolites

โœ Scribed by Joseph K. Suzuki; Aija Zirnis; Albert A. Manian


Book ID
112123874
Publisher
Journal of Heterocyclic Chemistry
Year
1976
Tongue
English
Weight
517 KB
Volume
13
Category
Article
ISSN
0022-152X

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The eyntheeie of 2-chloro-10-(3'-dimethylaminopropyl)phenothiazine-3', 3'-d2 (Chlorpromazine-d2) and ite four major metabolitee (the mono-and didemethylated aminee, chlorpromazine sulfoxide, and chlorpromazine N-oxide), all containing the 3',3'-d2 label in > 95% ieotopic purity, ie deecribed. Consid