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Synthesis of optically active lipidicα-amino acids and lipidic 2-amino alcohols

✍ Scribed by V. Constantinou-Kokotou; George Kokotos


Publisher
Springer
Year
1999
Tongue
English
Weight
698 KB
Volume
16
Category
Article
ISSN
0939-4451

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📜 SIMILAR VOLUMES


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A general methodology for the synthesis of saturated lipidic amino acids based on the oxidative cleavage of amino diols obtained by the regioselective opening of enantiomerically enriched 2,3-epoxy alcohols is described. The method opens the way to the synthesis of the enantiomers of lipidic 2-amino

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## Abstract The α‐amino acids with long alkyl side chains, the so‐called lipidic amino acids 1a–e, and their homo‐oligomers, the lipidic peptides 1p–aj, represent a class of compounds which combine the structural properties of peptides and proteins with the characteristics of lipids and membranes.