Stereoselective Synthesis of β-Amino Alcohols from Optically Active α-Amino Acids
✍ Scribed by Prof. Dr. Manfred T. Reetz; Mark W. Drewes; Alfred Schmitz
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 339 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0044-8249
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Polycondensations of dicarboxylic acids with diols having amide moieties derived from optically active amino alcohols were carried out. Polymers with M V n s 8,700- 17,400 were obtained by the polycondensations using 1.2 eq. of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDCrHCl) i
## Abstract This account concentrates on our new methodologies for the synthesis of fluorine analogues of amino acids and their derivatives using the Reformatsky‐type reactions of ethyl bromodifluoroacetate and ethyl dibromofluoroacetate with imines promoted by the Wilkinson catalyst. First, we pre