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Synthesis of Optically Active Isothiazole Derivatives fromL-(α)-Amino Acids

✍ Scribed by Dariusz Cież; E. Szneler


Book ID
106213574
Publisher
Springer Vienna
Year
2005
Tongue
English
Weight
156 KB
Volume
136
Category
Article
ISSN
0026-9247

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Practical synthesis of optically active
✍ Joëlle Viret; Jacqueline Gabard; André Collet 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 290 KB

Simple amino acids (1) can be converted in fair to good yield into hydrazino acids (3) of like configuration by using KOCI instead of NaOCl to promote the Shestakov rearrangement of the intermediate hydantoic acids (2). It was shown fifteen years ago by Karady et al.,' and later by Custafsson,' that