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Synthesis of New Aromatic (C17−C20)-Locked Side-Chain Analogues of Calcitriol (1α,25-Dihydroxyvitamin D 3 ) †,1

✍ Scribed by Fernández-Gacio, Ana; Vitale, Cristian; Mouriño, Antonio


Book ID
120558745
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
97 KB
Volume
65
Category
Article
ISSN
0022-3263

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✍ Freek Vrielynck; Dirk Van Haver; Maurits Vandewalle; Lieve Verlinden; Annemieke 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 681 KB

## Abstract The discovery that 1α,25‐dihydroxyvitamin D~3~ is effective in the inhibition of cellular proliferation and in the induction of cellular differentiation has led to a search for analogues in which these activities and the classical calcemic activity of the hormone are dissociated. In thi