Synthesis of Tetracyclic Analogues of Calcitriol (1α,25-Dihydroxyvitamin D3) with Side-Chain-Locked Spatial Orientations at C(20)
✍ Scribed by Carmen Varela; Kristina Nilsson; Mercedes Torneiro; Antonio Mouriño
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- German
- Weight
- 152 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0018-019X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract An improved synthetic route to 1α,25‐dihydroxyvitamin D~3~ des‐side chain analogues **2 a** and **2 b** with substituents at C18 is reported, along with their biological activity. These analogues display significant antiproliferative effects toward MCF‐7 breast cancer cells and prodiffe