Synthesis, Structure, and Biological Act
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Dr. Lieve Verlinden; Prof. Annemieke Verstuyf; Dr. Guy Eelen; Prof. Roger Bouill
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Article
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2011
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John Wiley and Sons
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English
⚖ 375 KB
👁 1 views
## Abstract An improved synthetic route to 1α,25‐dihydroxyvitamin D~3~ des‐side chain analogues **2 a** and **2 b** with substituents at C18 is reported, along with their biological activity. These analogues display significant antiproliferative effects toward MCF‐7 breast cancer cells and prodiffe