𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Testing of 2α-Modified 1α,25-Dihydroxyvitamin D3 Analogues with a Double Side Chain: Marked Cell Differentiation Activity.

✍ Scribed by Yoshitomo Suhara; Atsushi Kittaka; Seishi Kishimoto; Martin J. Calverley; Toshie Fujishima; Nozomi Saito; Takayuki Sugiura; Keizo Waku; Hiroaki Takayama


Publisher
John Wiley and Sons
Year
2003
Weight
200 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis, Structure, and Biological Act
✍ Dr. Lieve Verlinden; Prof. Annemieke Verstuyf; Dr. Guy Eelen; Prof. Roger Bouill 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 375 KB 👁 1 views

## Abstract An improved synthetic route to 1α,25‐dihydroxyvitamin D~3~ des‐side chain analogues **2 a** and **2 b** with substituents at C18 is reported, along with their biological activity. These analogues display significant antiproliferative effects toward MCF‐7 breast cancer cells and prodiffe