✦ LIBER ✦

Synthesis of mutagenic 2,4-dinitro-[7-14C]benzaldehyde

✍ Scribed by Miki Shoji; Masa-Aki Mori; Michio Sayama; Hiroshi Kozuka; Takashi Honda

Publisher: John Wiley and Sons
Year: 1994
Tongue: French
Weight: 228 KB
Volume: 34
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580340703

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

2,4‐Dinitro‐[7‐^14^C]benzaldehyde (4), a mutagenic substance which may have an unique metabolic activating pathways, was synthesized as a tracer for the detection of adducts of 4 with macromolecules. The preparation was performed in four steps from [7‐^14^C]toluene to give an overall radiochemical yield of 20% after purifying by TLC. The radiochemical purity was over 98%.

📜 SIMILAR VOLUMES

Synthesis [4-14C]- and [6,7-D2]trilostan

Synthesis [4-14C]- and [6,7-D2]trilostane

✍ D. Jonston; D. Elder 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 295 KB

## SLmrarY A synthetic procedure for producing [6.7-d2]trilostane is described. The synthesis was accomplished in 6 steps from androsta-4,6-dien-3,17-dione with the label being introduced by catalytic deuteration. The synthetic procedure, using [4-14Cltestosterone, gave the required ~d ~~l t r i ~

Synthesis of DL-[7-14C]indospicine and D

Synthesis of DL-[7-14C]indospicine and DL-2-amino[7-14C]pimelic acid

✍ Elzbieta Wieczorkowska; Mervyn P. Hegarty 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 322 KB

A new method of synthesis of DL-[ 7-14C]indospicine and DL-2-amino-[ 7-1 4C]pimelic acid and their nonradioactive equivalents is reported. The combined radiochemical yield of both compounds, starting from potassium 1 14C]cyanide was 15.3%. Indospicine was isolated as the flavianate.

Synthesis of 5-Nitro-1,2,3,4-tetrahydro-

Synthesis of 5-Nitro-1,2,3,4-tetrahydro-1,4-phthalazinedione and 1,8-Dinitro-5,7,12,14-tetrahydrophthalazino [2,3-b]phthalazine-5,7,12,14-tetraone.

✍ V. V. Ganzha; A. D. Kotov; T. V. Kesareva; V. Yu. Orlov 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 16 KB 👁 1 views

Synthesis of 4-|2-(dimethylamino) ethyl-

Synthesis of 4-|2-(dimethylamino) ethyl-2-14C| phenol (hordenine-α-14C)

✍ C. A. Russo; E. G. Gros 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 152 KB

## Abstract 4‐|2‐(Dimethylamino)ethyl‐2‐^14^C| phenol (hordenine‐α‐^14^C) has been synthesised in three steps from |^14^C|potassium cyanide and __p__‐benzyloxybenzyl chloride which in turn was obtained in four steps from __p__‐hydroxybenzoic acid.

Synthesis of 5,5-dimethyl-2,4-oxazolidin

Synthesis of 5,5-dimethyl-2,4-oxazolidinedione-2-C14 (DMO-2-C14)

✍ Thomas C. Butler; Jack D. Davidson 📂 Article 📅 1963 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB 👁 1 views

Synthesis of 1,2,6,7-14C-chelidonic acid

✍ J. Bergman; J. R. Gear 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 126 KB

## Abstract A semimicro synthesis was devised to prepare pure 1,2,6,7‐^14^C‐chelidonic acid of high specific activity from 1,2‐^14^C‐oxalic acid.