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Synthesis [4-14C]- and [6,7-D2]trilostane

✍ Scribed by D. Jonston; D. Elder

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
295 KB
Volume
27
Category
Article
ISSN
0022-2135

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✦ Synopsis

SLmrarY

A synthetic procedure for producing [6.7-d2]trilostane is described. The synthesis was accomplished in 6 steps from androsta-4,6-dien-3,17-dione with the label being introduced by catalytic deuteration. The synthetic procedure, using [4-14Cltestosterone, gave the required ~d ~~l t r i ~o s t a n e in four steps.

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