Boc-Tyr-D-Ala-Gly was prepared by catalytic tritiation of protected, iodinated tripeptide. The protected tritiated tripeptide and the Phe-Leu-CH2C1 dipeptide were condensed by the mixed anhydride method. The p r o - 3 " tecting group was removed by HC1-methanol. The /JH/-DALECK had a specific activi
Synthesis of high specific active tritiated Leu-enkephalin in the leucine residue
โ Scribed by S. Baba; H. Hasegawa; Y. Shinohara
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 396 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Tritiated methoxamine with a specific activity of 28.5 Ci/mmol was prepared by iodination of methoxamine followed by catalytic tritiation.
D-Ma2, D-Leu51Enkephalin (DADLE) labelled with tritium in the 2,6-positions of N-terminus tyrosine residue has been prepared. Synthesis of the precursor peptide, [2,6-dibromo-Tyrl]DADLE, was performed by solid phase synthesis using F'moc strategy. The peptide was tritiated catalytically to yield [2
## Abstract Thirteen peptides, analogues of bradykinin (BK), enkephalin, Substance P (SP) and [Sar^1^]โangiotensin II ([Sar^1^]โAT~II~) have been synthesized by the solidโphase method. In all these peptides the residue Phe and Tyr were substituted with the boronโcontaining aminoโacid Lโ__o__โcarbor