Synthesis of Elenic Acid, an Inhibitor of Topoisomerase II. -Stereospecific synthesis of title compound (VII) is achieved in five steps and an overall yield of 26% from iodophenol (I) and eicosyne (II), involving novel zipper reaction of alkyne (III) and one-pot elaboration of the terminal alkyne i
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Synthesis of Elenic Acid, an Inhibitor of Topoisomerase II
β Scribed by Hoye, Rebecca C.; Baigorria, Alejandro S.; Danielson, Michael E.; Pragman, Alexa A.; Rajapakse, Hemaka A.
- Book ID
- 126394136
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 100 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3263
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