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Synthesis of DNA fragments by the hydroxybenzotriazole phosphotriester approach

✍ Scribed by J.E. Marugg; M. Tromp; P. Jhurani; C.F. Hoyng; G.A. Van Der Marel; J.H. Van Boom


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
739 KB
Volume
40
Category
Article
ISSN
0040-4020

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## Abstract Application of the phosphorylating agent 2‐chlorophenyl‐0,0‐bis(1‐hydroxybenzotriazolyl)‐phosphate enabled us to synthesize DNA fragments (e.g., d‐AGGATCCT and d‐GTTCGG) on a polystyrene solid support:

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