A new method of synthesis of DL-[ 7-14C]indospicine and DL-2-amino-[ 7-1 4C]pimelic acid and their nonradioactive equivalents is reported. The combined radiochemical yield of both compounds, starting from potassium 1 14C]cyanide was 15.3%. Indospicine was isolated as the flavianate.
Synthesis of dl-Adrenalin-β-C 14 and dl-Adrenochrome-β-C 14
✍ Scribed by Schayer, Richard W.
- Book ID
- 126067588
- Publisher
- American Chemical Society
- Year
- 1952
- Tongue
- English
- Weight
- 169 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0002-7863
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D L -t y r o ~i n e -4 -~~C has been synthesized with an overall yield 29.3 based on phenol-1-14C as the starting material. Anisole-l-14C was prepared by methylation of phenol-1-14C with dimethyl sulfate. The radioactive anisole was then converted to p-anisaldehyde-4-14C by a modijied Gattermann rea
The causes of carnitine deficiency syndromes are not completely understood, but decomposition of L-carnitine in vivo is likely t o be involved. Carnitine is metabolized to y-butyrobetaine, and crotonobetaine is probably an intermediate in this pathway. To validate experimentally the precursor-produc
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