✦ LIBER ✦

Synthesis of DL-tyrosine-4-14C

✍ Scribed by J. H. Kim; C. R. Creger; J. R. Couch

Publisher: John Wiley and Sons
Year: 1969
Tongue: French
Weight: 391 KB
Volume: 5
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2590050106

No coin nor oath required. For personal study only.

✦ Synopsis

D L -t y r o ~i n e -4 -~~C has been synthesized with an overall yield 29.3 based on phenol-1-14C as the starting material. Anisole-l-14C was prepared by methylation of phenol-1-14C with dimethyl sulfate. The radioactive anisole was then converted to p-anisaldehyde-4-14C by a modijied Gattermann reaction and then condensed with hydantoin io give 5-(4-methoxybenzylidene-4-~4C) hydantoin. The hydantoin was then converted into DL-tyrosine-4-14C.

📜 SIMILAR VOLUMES

Synthesis of DL-[7-14C]indospicine and D

Synthesis of DL-[7-14C]indospicine and DL-2-amino[7-14C]pimelic acid

✍ Elzbieta Wieczorkowska; Mervyn P. Hegarty 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 322 KB

A new method of synthesis of DL-[ 7-14C]indospicine and DL-2-amino-[ 7-1 4C]pimelic acid and their nonradioactive equivalents is reported. The combined radiochemical yield of both compounds, starting from potassium 1 14C]cyanide was 15.3%. Indospicine was isolated as the flavianate.

Synthesis of [methyl-14C]crotonobetaine

Synthesis of [methyl-14C]crotonobetaine from DL-[methyl-14C]carnitine

✍ Heinz Löster; Hermann Seim 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 311 KB 👁 1 views

The causes of carnitine deficiency syndromes are not completely understood, but decomposition of L-carnitine in vivo is likely t o be involved. Carnitine is metabolized to y-butyrobetaine, and crotonobetaine is probably an intermediate in this pathway. To validate experimentally the precursor-produc

Synthesis of pethidine derivatives : 14C

Synthesis of pethidine derivatives : 14C labelled DL-phenoperidine

✍ C. Luu Duc; Cl. Charlon; Cl. Agnius Delord; J. Cros; B. Monsarrat 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 149 KB 👁 1 views

The phenoperidine hydrochloride was labelled with l4C at the carboethoxy group, in six steps from diethanolamine. The carbon-14 labelled benzyl cyanide precursor was prepared from Na CN and benzyl chloride 14

Synthesis of dl-amphetamine sulfate labe

Synthesis of dl-amphetamine sulfate labeled with C14

✍ Wilson, James W. 📂 Article 📅 1950 🏛 Elsevier ⚖ 167 KB

Synthesis of carbon-14 labeled [1-14C]-,

Synthesis of carbon-14 labeled [1-14C]-, and [2-14C]-L-tyrosine

✍ W. Augustyniak; R. Kański; M. Kańska 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 96 KB 👁 1 views

## Abstract Two labeled isotopomers of L‐tyrosine, L‐Tyr, have been synthesized using specific properties of the enzymes phenylanine ammonia lyase, PAL, and L‐phenylalanine hydroxylase. In an intermediate step [1‐^14^C]‐, and [2‐^14^C]‐L‐phenylalanine, L‐Phe, have been obtained from [1‐^14^C]‐, and

An efficient synthesis of [ring-14C]-L-t

An efficient synthesis of [ring-14C]-L-tyrosine from [U-14C]-phenol

✍ John T. Kendall 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 232 KB 👁 1 views