The synthesis of D,-clenbuterol (I) and D,-clenbuterol ( ) is described. D,-clenbuterol (I) was prepared from 4-amino-a-bromo-3,5-dichloroacetophenone by reaction with D,-tert-butylamine followed by reduction of the keto group with NaBH,. D,-clenbuterol (11) was prepared from 4-amino-cl-tert-butylam
Synthesis of deuterated mosapride citrate
β Scribed by Shiro Kato; Yoshimi Hirokawa
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- French
- Weight
- 245 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-2135
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β¦ Synopsis
Abstract
The deuterium labeled form of mosapride citrate, a potential gastroprokinetic agent, was prepared via reduction of ethyl 4β(4βfluorobenzyl)β2βmorpholinecarboxylate (4) with lithium borodeuteride.
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Pentacene-d14, pentacene-d and pentacene-d4 were obtained from 6,13-pentacenequinone-d 'grid 6,13-pentacenequinone-d4 by refluxing with aluminumcyhfohexoxide-d o r aluminumcyclohexoxide. The former quinones were prepared from 1,2-benzenedicarboxalde- hyde-d o r 1,2-benzenedicarboxa1dehyde-d2 and 1,4
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