Synthesis of deuterated decalin

Synthesis of deuterated clenbuterol

✍ Ole Jørgensen; Helge Egsgaard; Elfinn Larsen 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 464 KB

The synthesis of D,-clenbuterol (I) and D,-clenbuterol ( ) is described. D,-clenbuterol (I) was prepared from 4-amino-a-bromo-3,5-dichloroacetophenone by reaction with D,-tert-butylamine followed by reduction of the keto group with NaBH,. D,-clenbuterol (11) was prepared from 4-amino-cl-tert-butylam

Synthesis of deuterated naproxens

✍ Peter M. Gannett; Laura Miller; Jonathan Daft; Charles Locuson; Timothy S. Tracy 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 91 KB

## Abstract A general scheme for the synthesis of (__S__)‐6‐methoxy‐2‐propanoic acid (naproxen) deuterated on the naphthyl ring, methoxy group, or both, is described. The resulting labeled naproxen derivatives are useful probes for examining atypical kinetics displayed by cytochrome P450 2C9. Copyr

Synthesis of deuterated pentacenes

✍ B. H. Kwant 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 217 KB

Pentacene-d14, pentacene-d and pentacene-d4 were obtained from 6,13-pentacenequinone-d 'grid 6,13-pentacenequinone-d4 by refluxing with aluminumcyhfohexoxide-d o r aluminumcyclohexoxide. The former quinones were prepared from 1,2-benzenedicarboxalde- hyde-d o r 1,2-benzenedicarboxa1dehyde-d2 and 1,4

Synthesis of deuterated dihydrochalcones

✍ Daniel J. Comeskey; Janine M. Cooney; Daryl D. Rowan 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 128 KB

The dihydrochalcones phloretin and phloridzin are major phenolic constituents of apple fruit. Phloretin-d 4 , deuterated at both the a and b positions, was prepared by hydrogenolysis of naringenin and by deuterium exchange from unlabelled phloretin using Pd/C and sodium formate with methanol-d 1 as

Synthesis of Deuterated Mevalonolactone

Synthesis of Deuterated Mevalonolactone Isotopomers

✍ Jeroen S. Dickschat; Christian A. Citron; Nelson L. Brock; Ramona Riclea; Hennin 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 217 KB

## Abstract A synthetic route was developed for the preparation of deuterated mevalonolactones. Using low‐cost deuterated reagents, this route allows for the independent introduction of deuterium labeling into any carbon position or into any combination of positions. Following this approach, the sy

Synthesis of deuterated isoflavone disul

Synthesis of deuterated isoflavone disulfates

✍ Otto Soidinsalo; Kristiina Wähälä 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 122 KB

## Abstract Efficient synthesis of polydeuterated di‐__O__‐sulfates of three isoflavones, daidzein (**1**), genistein (**2**), glycitein (**3**), is described. The isoflavones were first deuterated with CF~3~COOD under microwave irradiation to yield daidzein‐__d__~6~ (**4**), genistein‐__d__~4~ (**