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Synthesis of carbon-14 labeled 1,4-benzodiazepines. IV. Carbon-13 and carbon-14 labeled 8-chloro-1-(2-dimethylamino)ethyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepine tosylate

✍ Scribed by Richard S. P. Hsi; Wayne T. Stolle

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
341 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Carbon‐13 and carbon‐14 labeled forms of the title compound have been prepared from the correspondingly labeled forms of 8‐chloro‐1‐methyl‐6‐phenyl‐4H‐s‐triazolo[4,3‐a][1,4]benzodiazepine (3)Alprazolam is the generic USAN name for this compound.

. A modified and more convenient version of the previously reported procedure for preparing 3 is described.

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