## Abstract Two labeled isotopomers of L‐tyrosine, L‐Tyr, have been synthesized using specific properties of the enzymes phenylanine ammonia lyase, PAL, and L‐phenylalanine hydroxylase. In an intermediate step [1‐^14^C]‐, and [2‐^14^C]‐L‐phenylalanine, L‐Phe, have been obtained from [1‐^14^C]‐, and
Synthesis of C-14 Carboxyl-labeled Tyrosine and Diiodotyrosine 1
✍ Scribed by Loftfield, Robert Berner
- Book ID
- 126282334
- Publisher
- American Chemical Society
- Year
- 1950
- Tongue
- English
- Weight
- 270 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0002-7863
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## Abstract The synthesis of selectively ^14^C‐labeled l‐tryptophan and its derivative 5‐hydroxy‐l‐tryptophan using chemical and multienzymatic methods is reported. The mixture containing [1‐^14^C[‐dl‐alanine, indole or 5‐hydroxyindole has been converted to [1‐^14^C]‐l‐tryptophan or 5′‐hydroxy‐[1‐^