𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of [14C] labeled 2-methoxypyrimidine-5-carboxylic acid

✍ Scribed by Akula Murthy; Giliyar Ullas


Publisher
John Wiley and Sons
Year
2009
Tongue
French
Weight
110 KB
Volume
52
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

A versatile method for ^14^C labeling of 2‐methoxypyrimidine‐5‐carboxylic acid at the 2‐position has been developed after encountering difficulties with traditional approaches to label the carboxyl function. The method developed can also be used for ^14^C labeling other positions of the pyrimidine ring system. Copyright © 2009 John Wiley & Sons, Ltd.


📜 SIMILAR VOLUMES


Synthesis of 14c-labeled 2,2-dichloropro
✍ F. S. Tanaka; R. G. Wien 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 413 KB 👁 1 views

## Abstract A widely used herbicide, 2,2‐dichloropropionic acid (dalapon), was synthesized with ^14^C‐labeling in the C‐1 or C‐2 positions. The carboxyl labeled material was prepared in 55% yield by carbonation of 1,1‐dichloro‐ethyllithium at approximately −104°. Starting with trichloroacetic acid,

Synthesis of [13C5] and [carbonyl-14C]-5
✍ Peter N. Dorff; Mark E. Powell; Charles S. Elmore 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 88 KB

## Abstract The inventory of labeled compounds and methods for their preparation are constantly growing, but still more building blocks of biologically relevant compounds need to be developed. Furans are frequently encountered in bioactive molecules, and a good synthesis of labeled furan is found i

Synthesis of 5-amino[carboxyl-14C]salicy
✍ Ole Jørgensen; Susanne Petersen; Lars Carlsen 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 121 KB

Improvements have baen made to the synthesis of 5-aminasalicylic wid (S-ASA) in order to make it applicable for the small-scale synthesis of 5-smidcerboxvl-l ~l s a l i c y l i c acid.