๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of 9-hydroxypurines: Intermediates to novel antiviral acyclonucleosides

โœ Scribed by M.R. Harnden; P.G. Wyatt


Book ID
103403548
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
193 KB
Volume
31
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Synthesis of 9-(hydroxyalkylamino)guanin
โœ M.R. Harnden; R.L. Jarvest ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 177 KB

9-Aminoguanine (3) has been prepared and used as an intermediate in syntheses of 9-(3-hydroxypropylanino)guazne (id) and 9-[3-hydroxy-2-(hydroxymethyl)propylanino]guanine (le), the first reported members of a new series of antiviral acyclonucleosides. Certain 9-alkylated guanines such as acyclovirl,

ChemInform Abstract: Synthesis and Antiv
โœ Stephen C. Bergmeier; Susan L. Fundy; John C. Drach ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 1 views

Synthesis and Antiviral Activity of Novel Aza-acyclonucleosides. -Using Mitsunobu coupling conditions the novel title compounds (VII) and (IX) are prepared.Surprisingly, they are avoid of any antiviral activity.

An improved synthesis of the antiviral a
โœ M.R. Harnden; R.L. Jarvest ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 185 KB

Alkylation of 2-amino-6-chloropurine with 5-(2-bromoethyl)-2,2dimethyl-1,3-dioxan ( 7) and subsequent acid hydrolysis provides an improved procedure for synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3hydroxymethylbut-I-yl)guanine (3).