✦ LIBER ✦

An improved synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine

✍ Scribed by M.R. Harnden; R.L. Jarvest

Book ID: 104229162
Publisher: Elsevier Science
Year: 1985
Tongue: French
Weight: 185 KB
Volume: 26
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)99010-5

No coin nor oath required. For personal study only.

✦ Synopsis

Alkylation of 2-amino-6-chloropurine with 5-(2-bromoethyl)-2,2dimethyl-1,3-dioxan ( 7) and subsequent acid hydrolysis provides an improved procedure for synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3hydroxymethylbut-I-yl)guanine (3).

📜 SIMILAR VOLUMES

Synthesis and evaluation of 2-amino-6-fl

Synthesis and evaluation of 2-amino-6-fluoro-9-(4-hydroxy-3-hydroxymethylbut-1-yl)purine mono- and diesters as potential prodrugs of penciclovir

✍ Dae-Kee Kim; Namkyu Lee; Hun-Taek Kim; Guang-Jin Im; Key H Kim 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 178 KB

Prodrugs of the selective antiherpesviru

Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties

✍ Harnden, Michael R.; Jarvest, Richard L.; Boyd, Malcolm R.; Sutton, David; Vere 📂 Article 📅 1989 🏛 American Chemical Society 🌐 English ⚖ 866 KB

An Improved Total Synthesis of PET HSV-t

An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[18F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]FHPG).

✍ Qi-Huang Zheng; et al. et al. 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 66 KB

2004 Nucleic acids Nucleic acids U 0700 An Improved Total Synthesis of PET HSV-tk Gene Expression Imaging Agent 9-[(3-[ 18 F]Fluoro-1-hydroxy-2-propoxy)methyl]guanine ([ 18 F]FHPG). -(ZHENG\*, Q.-H. ; et al.; Synth. Commun. 34 (2004) 5, 917-932; Dep. Radiol.,

AN IMPROVEMENT IN THE SYNTHESIS OF 1,2,4

AN IMPROVEMENT IN THE SYNTHESIS OF 1,2,4,9-TETRAHYDROCARBAZOL-3-ONE

✍ Boulanger, William A.; Dolsen, Victoria 📂 Article 📅 1993 🏛 Taylor and Francis Group 🌐 English ⚖ 119 KB

ChemInform Abstract: [9 + 9 + 9] Synthes

ChemInform Abstract: [9 + 9 + 9] Synthesis of N,N′-Bis(4-methyloxazol-5-yl)urea (III) as the Key Building Block of 1,3-Bis(4-methyloxazol-5-yl)xanthine Towards an Improved Bronchodilator.

✍ Sibdas Ray; Sukla Ghosh 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

An Improved Total Synthesis of PET HSV‐t

An Improved Total Synthesis of PET HSV‐tk Gene Expression Imaging Agent 9‐[(3‐[ 18 F]Fluoro‐1‐hydroxy‐2‐propoxy)methyl]guanine ([ 18 F]FHPG)

✍ Wang, Ji‐Quan; Zheng, Qi‐Huang; Fei, Xiangshu; Liu, Xuan; Gardner, Thomas A.; Ka 📂 Article 📅 2004 🏛 Taylor and Francis Group 🌐 English ⚖ 202 KB