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Synthesis of Novel Acyclonucleosides Analogs of Pyridothienopyrimidine as Antiviral Agents

✍ Scribed by El-Essawy, Farag A.

Book ID
126162598
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
183 KB
Volume
24
Category
Article
ISSN
0732-8311

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9-Aminoguanine (3) has been prepared and used as an intermediate in syntheses of 9-(3-hydroxypropylanino)guazne (id) and 9-[3-hydroxy-2-(hydroxymethyl)propylanino]guanine (le), the first reported members of a new series of antiviral acyclonucleosides. Certain 9-alkylated guanines such as acyclovirl,