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Synthesis of Novel Isothionucleosides as Potential Antiviral Agents

✍ Scribed by Jonas Brånalt; Gunilla Niklasson; Ingemar Kvarnström; Björn Classon; Bertil Samuelsson


Publisher
Springer
Year
1998
Weight
128 KB
Volume
2
Category
Article
ISSN
1433-1373

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Synthesis of bicarbocyclic dideoxynucleo
✍ Qi Chao; Vasu Nair 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 707 KB

Two novel classes of bicarbocyclic dideoxynucleosides have been synthesized for antiviral studies. The key intermediates, 9 and 23, synthesized in multiple steps from readily available monocyclic or bicyclic precursors, were coupled with the desired heterocyclic bases to afford, after further elabor