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Synthesis of 7-D-mandel-β-14C-amino-3-{[(1-methyl-1H-tetrazol-5-yl)-thio]methyl}-3-cephem-4-carboxylic acid (cefamandole-14C)

✍ Scribed by H. Minato; T. Nagasaki; Y. Katsuyama; M. Hamada; R. Kiritani

Publisher: John Wiley and Sons
Year: 1978
Tongue: French
Weight: 272 KB
Volume: 14
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580140321

No coin nor oath required. For personal study only.

✦ Synopsis

Cefamandole, 7-D-mandelamino-3-{ [(l-methyl-lH-tetrazo1-5-yl)-thio]methyl}-3-cephem-4-carboxylic acid (I), is a new semisynthetic, parenteral cephalosporin antibiotic with a broad antibacterial spectrum, synthesized by the Lilly Research Laboratories.

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