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Synthesis of (5-methyl-2-oxo-1,3-dioxol-4-YL)methyl 7-[D-O-(L-alanyl)[β-14C]mandelamido]-3-[[(5-methyl-1,3,4-thiadiazol-2-YL)thio]methyl]-3-cephem-4-carboxylate and its active compound

✍ Scribed by Susumu Nishizawa; Hiroshi Matsui; Akio Ohkubo; Nobuharu Kakeya; Reiko Kiritani


Publisher
John Wiley and Sons
Year
1988
Tongue
French
Weight
232 KB
Volume
25
Category
Article
ISSN
0022-2135

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Synthesis of 7-D-mandel-β-14C-amino-3-{[
✍ H. Minato; T. Nagasaki; Y. Katsuyama; M. Hamada; R. Kiritani 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 272 KB 👁 1 views

Cefamandole, 7-D-mandelamino-3-{ [(l-methyl-lH-tetrazo1-5-yl)-thio]methyl}-3-cephem-4-carboxylic acid (I), is a new semisynthetic, parenteral cephalosporin antibiotic with a broad antibacterial spectrum, synthesized by the Lilly Research Laboratories.