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Synthesis and Antibacterial Activities of 4-Amino-3-(1-aryl-5-methyl-1,2,3-triazol-4-yl) -5-mercapto-1, 2,4-triazoles/2- Amino-5-(1-aryl-5-methyl-1,2,3-triazol-4-yl)-1,3,4-thiadiazoles and Their Derivatives

โœ Scribed by Yan Zhang; Xiao-Wen Sun; Xin-Ping Hui; Zi-Yi Zhang; Qin Wang; Qi Zhang


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
338 KB
Volume
20
Category
Article
ISSN
0256-7660

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The Schiff bases 3a-h obtained from 4-amino-1,2,4-triazol-3-ones 1a-h when subjected to Japp-Klingemann reaction yielded the corresponding 3-{2-[(2-aryl-5-methyl-3H-[1,2,4]-triazol-3-one-4-yl)]-iminophenyl}-pentane-2,4-diones 4 a-h. These diones on cyclisation with N 2 H 4 yielded the title compound