𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 6,7-dehydro-5-oxo-prostaglandin I1: A stable analog of prostacyclin

✍ Scribed by Hisao Nishiyama; Kiyotaka Ohno


Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
190 KB
Volume
20
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of new stable analogues of pro
✍ C.W. Bird; H.I. Butler; M.P.L. Caton; E.C.J. Coffee; C.J. Hardy; T.W. Hart; H.J. 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 203 KB

The synthesis is described of (fi)-6a-oxo-6,9-methano-L5-hydroxyprosta-5,13-dienoic acids as stable analogues of prostacyclin with blood platelet aggregation inhibiting activity. Considerable effort has been devoted to the preparation of chemically stable analogues prostacyclin.' We report here the

An improved synthesis of 5,6,7,8-tetrahy
✍ Robert L. Dow; Steven R. Schneider 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 29 KB

## Abstract The 5,6,7,8‐tetrahydro‐1,7‐naphthyridine (**7**) pharmacophore has the potential to serve as a confor‐mationally‐locked analog of the pharmacologically active 2‐(3‐pyridyl)ethylamine (**1**) core structure. This paper describes the synthesis of 5,6,7,8‐tetrahydro‐1,7‐naphthyridine (**7*

Studies on asymmetric synthesis of hyper
✍ Xu-Chang He; Bin Wang; Donglu Bai 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 234 KB

A bridged bicyclic coml~)und 8. the key intermediate for the synthesis of huperzine A (1). was prepared by asymmetric palladium-calalyzed bicycloannulation of g-keto ester 2. A variety of chhal ligands and reaction conditions were tcsled. 52% ee values were observed.

Synthesis of bridged analogs of epibatid
✍ Lawrence E Brieaddy; S Wayne Mascarella; Hernán A Navarro; Robert N Atkinson; M. 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 86 KB

The synthesis of conformationally locked analogs of epibatidine are described in which the key step is an intramolecular reductive palladium-catalyzed Heck-type coupling.