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Synthesis of 3-Methoxy-5-oxo-6-phenyl-5,6-dihydro-4H-isothiazolo[5,4-b]-1,4-thiazine 7,7-Dioxide, the First Representative of a New Heterocyclic System.

โœ Scribed by N. V. Voskoboev; A. I. Gerasyuto; S. G. Zlotin


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
33
Category
Article
ISSN
0931-7597

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โœ Yehia A. Ibrahim; Ahmed H. M. Elwahy; Ayman E. M. El-Fiky ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 319 KB

The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines