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Synthesis of 5S,12S - diHETE (LTBx)

✍ Scribed by Julian Adams; Yves Leblanc; Joshua Rokach


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
205 KB
Volume
25
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


A new efficient synthesis of (5S,12S)-Di
✍ D. Chemin; M. Alami; G. Linstrumelle πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 French βš– 235 KB

An efficient synthesis of (SS,12S)-diHETE was realized by a Pd-Cu catalysed coupling

Total synthesis of (11R, 12S)-diHETE
✍ AgnΓ¨s Gigou; Jean-Pierre Beaucourt; Jean-Paul Lellouche; RenΓ© Gree πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 French βš– 205 KB

The first total synthesis of (1 lR, 12s) diHETE IS reported. The key step is the highly chemioand stereaselective osmylation of a double bond in a trienyne system selectively complexed by an Fe(CO)3 group.

Stereospecific total synthesis of (5.6)-
✍ Claude Kugel; Jean-Paul Lellouche; Jean-Pierre Beaucourt; Gilles Niel; Jean-Pier πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 273 KB

The fist highly practical stereocontrolled synthesis of the four diastereoisomeric (5,6)-DiHETEs is described using the acetonides of D-and L-glyceraldehyde as a source of chirality. Their spectral and physico-chemical properties are also described. Although known for some years as non enzymatic hy

Synthesis of 12(S),20-, 12(S),19(R)-, an
✍ Sukumar Manna; Jacques Viala; Pendri Yadagiri; J.R Falck πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science 🌐 French βš– 231 KB

Enantiospecific syntheses of the ZO-and both 19-hydroxy metabolites of 12(S)-HETE were accomplished using readily available, chiral precursors. Recently, a new metabolite of 12(S)-hydroxyeicosatetraenoic (12-HETE) acid (1) was isolated from the coincubation of human platelets and neutrophils with ar