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Synthesis of [3H-pyroglutamyl1]-adipokinetic hormone-1

✍ Scribed by A. N. Starratt; L. E. King; B. G. Loughton

Publisher: John Wiley and Sons
Year: 1996
Tongue: French
Weight: 361 KB
Volume: 38
Category: Article
ISSN: 0022-2135
DOI: 10.1002/(sici)1099-1344(199612)38:12<1139::aid-jlcr932>3.0.co;2-2

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✦ Synopsis

L-[3,4-'H(N)]-Glutamine was cyclized to ['HI-pyroglutamic acid and coupled with [des-pGlu']-AKH-I to give [3H-pyroglutamy11]-adipokinetic hormone-I with a specific activity of 46 Ci/mmole. Results relating to stability of this product during storage are reported.

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