𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 3-fluoro azetidinone by electrophilic fluorination

✍ Scribed by Jean-Pierre Genêt; Jean-Olivier Durand; Sylvain Roland; Monique Savignac; Frédéric Jung

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
200 KB
Volume
38
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

An easy access to the 3-fluoroazetidinone 4a based on electrophilic fluorination, is reported. The fluorination of the ~l-lactam 7 with Differding's N-fluorosulfonimide proceeds stereoselectively, under mild conditions and in good yield.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of 3-Fluo
ChemInform Abstract: Synthesis of 3-Fluoro Azetidinone by Electrophilic Fluorination.
✍ J.-P. GENET; J.-O. DURAND; S. ROLAND; M. SAVIGNAC; F. JUNG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Synthesis of 3-Fluoro Azetidinone by Electrophilic Fluorination. -The title compound (V) is obtained stereoselectively under mild conditions and in good yield as potential intermediate for the synthesis of new antibiotics. It is noteworthy that fluoropyridinium triflates and Barnette's N-fluorosulfo

Synthesis of fluorinated azetidinones
Synthesis of fluorinated azetidinones
✍ Roger Joyeau; Huguette Molines; Michel Wakselman 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 22 KB