ChemInform Abstract: Synthesis of 3-Fluoro Azetidinone by Electrophilic Fluorination.

✍ Scribed by J.-P. GENET; J.-O. DURAND; S. ROLAND; M. SAVIGNAC; F. JUNG

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199720107

✦ Synopsis

Synthesis of 3-Fluoro Azetidinone by Electrophilic Fluorination. -The title compound (V) is obtained stereoselectively under mild conditions and in good yield as potential intermediate for the synthesis of new antibiotics. It is noteworthy that fluoropyridinium triflates and Barnette's N-fluorosulfonamide are inefficient for the fluorination of compound (IV). -(GENET, J.-P.;