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Synthesis of 3- and 5-endo-(6-Chloro-3-pyridoxy)-methyl-2-azabicyclo[2.2.0]hexane and 3-endo-(6-Chloro-3-pyridoxy)-methyl-2-azabicyclo[2.2.0]hex-5-ene. ABT-594 Analogs

โœ Scribed by Grant R Krow; Jing Yuan; Yuhong Fang; Michael D Meyer; David J Anderson; Jeffrey E Campbell; Patrick J Carroll


Book ID
108371008
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
119 KB
Volume
56
Category
Article
ISSN
0040-4020

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Additions to cyclobutenes: synthesis of
โœ Donald H. Aue; Hisashi lwahashi; Dale F. Shellhamer ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 195 KB

As part of a study on additions to strained olefins and synthesis of strained nitrogen heterocycles, we have found that addition of methoxycsrbonylnitrene to 1,2dimethylcyclobutene, 2, and l-methylcyclobutene, 2, provides a convenient synthesis of the corresponding 5-azabicyclo[2.l.O]pentanes 2a and