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Additions to cyclobutenes: synthesis of 5-azabicyclo[2.1.0]pentanes, 2-azabicyclo[ 2.2.0]hexanes, and 1-azaspiro[3.3]heptanes

✍ Scribed by Donald H. Aue; Hisashi lwahashi; Dale F. Shellhamer

Publisher
Elsevier Science
Year
1973
Tongue
French
Weight
195 KB
Volume
14
Category
Article
ISSN
0040-4039

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✦ Synopsis

As part of a study on additions to strained olefins and synthesis of strained nitrogen heterocycles, we have found that addition of methoxycsrbonylnitrene to 1,2dimethylcyclobutene, 2, and l-methylcyclobutene, 2, provides a convenient synthesis of the corresponding 5-azabicyclo[2.l.O]pentanes 2a and 2b.

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