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Synthesis of 2-Azabicyclo[4.1.0]heptanes through Stereoselective Cyclopropanation Reactions

✍ Scribed by Irene Suárez del Villar; Ana Gradillas; Javier Pérez-Castells


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
347 KB
Volume
2010
Category
Article
ISSN
1434-193X

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Additions to cyclobutenes: synthesis of
✍ Donald H. Aue; Hisashi lwahashi; Dale F. Shellhamer 📂 Article 📅 1973 🏛 Elsevier Science 🌐 French ⚖ 195 KB

As part of a study on additions to strained olefins and synthesis of strained nitrogen heterocycles, we have found that addition of methoxycsrbonylnitrene to 1,2dimethylcyclobutene, 2, and l-methylcyclobutene, 2, provides a convenient synthesis of the corresponding 5-azabicyclo[2.l.O]pentanes 2a and