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Synthesis of 2- C -Methyl- d -erythritol 4-Phosphate: The First Pathway-Specific Intermediate in the Methylerythritol Phosphate Route to Isoprenoids

โœ Scribed by Koppisch, Andrew T.; Blagg, Brian S. J.; Poulter, C. Dale


Book ID
125950962
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
34 KB
Volume
2
Category
Article
ISSN
1523-7060

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Optically pure 2-C-methyl-d-erythritol 4-phosphate, a key intermediate in the mevalonate-independent route for isoprenoid biosynthesis, is conveniently synthesized from 1,2-O-isopropylidene-a-d-xylofuranose, including the possibility of radiolabeling of this substrate.

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