## Abstract [^13^C~2~]Nifedipine (3) was synthesized from [^13^C]methanol (&1macr;) in two steps. Copyright © 2003 John Wiley & Sons, Ltd.
Synthesis of [2′-13C]biotin
✍ Scribed by W. A. Etzel; S. Berger
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 194 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
[2′‐^13^C]Biotin was synthesized in 51% yield by reaction of the hydrolysis product of biotin, 3,4‐diaminotetrahydro‐2‐thiophenvalerianic acid, with [^13^C]phosgene.
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CIQuinoline and [3-Clquinoline were synthesised by a five-step process starting from isatin. Acetylation of isatin with acetyl chloride labelled in either the 1or 2-position, was followed by the Pfitzinger reaction to give 2-hydroxy-4-quinoline carboxylic acid labelled in the 2- or 3-position. Dec
## Abstract The synthesis of mevalonolactone with ^13^C‐labels at positions 2 and 3 is reported. Hydrolysis of methyl 3‐hydroxy‐3‐methyl‐5,5‐dimethoxy‐valerate‐2,3‐^13^C~2~ to the aldehydo acid followed by reduction with sodium borohydride yielded the title compound. The material is useful as a sub
## Abstract The first synthesis of doubly labeled, [2‐^13^C, 4‐^13^C]‐(2__R__,3__S__)‐catechin 15 and [2‐^13^C, 4‐^13^C]‐(__2R__,3__R__)‐epicatechin 18 starting from labeled 2‐hydroxy‐4, 6‐bis(benzyloxy)acetophenone 3 and labeled 3, 4‐bis(benzyloxy)‐benzaldehyde 7 are described. Copyright © 2010 Jo
13 13 [2-C]cyclohexanone was synthesized through [ Clcyanation of cyclopentanone followed by acetylation, reduction and ring expansion. Treatment with cupric bromide/lithium bromide and dehydrobromination of the resulting labeled 1,6-dibromohexanone in a "one pot" procedure gave [2-13C]phenol.