The presence of 2-deoxy-2-['sF]fluoro-D-mannose (['sF]FDM) in 2-deoxy-2-['\*F]fluoro-o-glucose (['aF]FDG) prepared by the reaction of 3,4,6-tri-0-acetyi-D-glucal (TAG) with ['\*F]acetyl hypofluorite ([r\*F]CHsCOOF) or ['sF]Fr was quantified by radio HPLC analysis of reacetylated ['\*F]FDG. The solve
Synthesis of 18F-labelled 2-deoxy-2-fluoro-d-galactopyranose using the acetyl hypofluorite procedure
✍ Scribed by Masao Tada; Taiju Matsuzawa; Keiichiro Yamaguchi; Yoshinao Abe; Hiroshi Fukuda; Masatoshi Itoh; Hiroshi Sugiyama; Tatsuo Ido; Toshihiro Takahashi
- Book ID
- 108309021
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 237 KB
- Volume
- 161
- Category
- Article
- ISSN
- 0008-6215
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A nucleophilic radiofluorination of methyl 3,4-0-isopropylidene-2-0-(trif luoromethanesulfonyl) -6-O-trityl-/3-D-talopyranoside (1) with aninopolyether Hydrolysis of 2 with 6N HCl followed by passage through an ion retardation resin column and a neutral alumina column gave 2-deoxy-2-[18F1 f luoro-