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Synthesis of 14C-hydroxyurea with immobilized 14C-cyanate

✍ Scribed by Alfred M. Ajami

Publisher
John Wiley and Sons
Year
1983
Tongue
French
Weight
173 KB
Volume
20
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A solution of hydroxylamine hydrochloride is passed over a column bed of Amberlite IRA‐400 pre‐loaded with ^14^CNO^−^ anions. ^14^C‐hydroxyurea is formed in 50% radiochemical yield after recrystallization. The product is not contaminated with iso‐hydroxyurea or other by‐products usually found in the reaction of hydroxylamine hydrochloride with aqueous potassium cyanate.

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