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Synthesis of 14C-lanosterol and 14C-desmosterol

✍ Scribed by B. Danieli; G. Russo


Publisher
John Wiley and Sons
Year
1965
Tongue
French
Weight
296 KB
Volume
1
Category
Article
ISSN
0022-2135

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✦ Synopsis


The synthesis of lanosterol [la] and desmosterol [Ira] Iabeled with 14C in the 25 position by a Wittig reaction between triphenyl-214C isopropylidene-phosphorane [IVb] and the corresponding aldehydes are described. The specijic activities obtained are, respectively, 0.539 mClmM and 0.752 mClmM and the purities of the compounds, respectively, 96 and 99 %.


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